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Investigating receptor-mediated antibody transcytosis using blood–brain barrier organoid arrays
BACKGROUND: The pathways that control protein transport across the blood–brain barrier (BBB) remain poorly characterized. Despite great advances in recapitulating the human BBB in vitro, current models are not suitable for systematic analysis of the molecular mechanisms of antibody transport. The ga...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454074/ https://www.ncbi.nlm.nih.gov/pubmed/34544422 http://dx.doi.org/10.1186/s12987-021-00276-x |