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Investigating receptor-mediated antibody transcytosis using blood–brain barrier organoid arrays

BACKGROUND: The pathways that control protein transport across the blood–brain barrier (BBB) remain poorly characterized. Despite great advances in recapitulating the human BBB in vitro, current models are not suitable for systematic analysis of the molecular mechanisms of antibody transport. The ga...

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Detalles Bibliográficos
Autores principales: Simonneau, Claire, Duschmalé, Martina, Gavrilov, Alina, Brandenberg, Nathalie, Hoehnel, Sylke, Ceroni, Camilla, Lassalle, Evodie, Kassianidou, Elena, Knoetgen, Hendrik, Niewoehner, Jens, Villaseñor, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454074/
https://www.ncbi.nlm.nih.gov/pubmed/34544422
http://dx.doi.org/10.1186/s12987-021-00276-x

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