CYT387, a potent IKBKE inhibitor, suppresses human glioblastoma progression by activating the Hippo pathway

Recent studies have showed that IKBKE is overexpressed in several kinds of cancers and that IKBKE-knockdown inhibits tumor progression. In this article, we first verified that two glioblastoma cell lines, U87-MG and LN-229, were sensitive to CYT387 by measuring the half maximal inhibitory concentrat...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Lu, Jie, Li, Jing, Liu, Yang, Guo, Gaochao, Huang, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454155/
https://www.ncbi.nlm.nih.gov/pubmed/34544426
http://dx.doi.org/10.1186/s12967-021-03070-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454155/
https://www.ncbi.nlm.nih.gov/pubmed/34544426
http://dx.doi.org/10.1186/s12967-021-03070-3

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