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CYT387, a potent IKBKE inhibitor, suppresses human glioblastoma progression by activating the Hippo pathway
Recent studies have showed that IKBKE is overexpressed in several kinds of cancers and that IKBKE-knockdown inhibits tumor progression. In this article, we first verified that two glioblastoma cell lines, U87-MG and LN-229, were sensitive to CYT387 by measuring the half maximal inhibitory concentrat...
Autores principales: | Wang, Xin, Lu, Jie, Li, Jing, Liu, Yang, Guo, Gaochao, Huang, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454155/ https://www.ncbi.nlm.nih.gov/pubmed/34544426 http://dx.doi.org/10.1186/s12967-021-03070-3 |
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