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Tauroursodeoxycholic acid alleviates secondary injury in spinal cord injury mice by reducing oxidative stress, apoptosis, and inflammatory response

BACKGROUND: Tauroursodeoxycholic acid (TUDCA) is a hydrophilic bile acid derivative, which has been demonstrated to have neuroprotective effects in different neurological disease models. However, the effect and underlying mechanism of TUDCA on spinal cord injury (SCI) have not been fully elucidated....

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Detalles Bibliográficos
Autores principales: Hou, Yonghui, Luan, Jiyao, Huang, Taida, Deng, Tiancheng, Li, Xing, Xiao, Zhifeng, Zhan, Jiheng, Luo, Dan, Hou, Yu, Xu, Liangliang, Lin, Dingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454169/
https://www.ncbi.nlm.nih.gov/pubmed/34544428
http://dx.doi.org/10.1186/s12974-021-02248-2