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Partial volume correction analysis for (11)C-UCB-J PET studies of Alzheimer’s disease

PURPOSE: (11)C-UCB-J PET imaging, targeting synaptic vesicle glycoprotein 2A (SV2A), has been shown to be a useful indicator of synaptic density in Alzheimer’s disease (AD). For SV2A imaging, a decrease in apparent tracer uptake is often due to the combination of gray-matter (GM) atrophy and SV2A de...

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Detalles Bibliográficos
Autores principales: Lu, Yihuan, Toyonaga, Takuya, Naganawa, Mika, Gallezot, Jean-Dominique, Chen, Ming-Kai, Mecca, Adam P., van Dyck, Christopher H., Carson, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454285/
https://www.ncbi.nlm.nih.gov/pubmed/34119639
http://dx.doi.org/10.1016/j.neuroimage.2021.118248