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Innate immune detection of lipid oxidation as a threat assessment strategy

Oxidized phospholipids that result from tissue injury operate as immunomodulatory signals that, depending on the context, lead to proinflammatory or anti-inflammatory responses. In this Perspective, we posit that cells of the innate immune system use the presence of oxidized lipids as a generic indi...

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Detalles Bibliográficos
Autores principales: Zhivaki, Dania, Kagan, Jonathan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454293/
https://www.ncbi.nlm.nih.gov/pubmed/34548649
http://dx.doi.org/10.1038/s41577-021-00618-8