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Hypercholesterolemia Impairs Clearance of Neutrophil Extracellular Traps and Promotes Inflammation and Atherosclerotic Plaque Progression

Hypercholesterolemia-induced NETosis and accumulation of neutrophil extracellular traps (NETs) in the atherosclerotic lesion exacerbates inflammation and is causally implicated in plaque progression. We investigated whether hypercholesterolemia additionally impairs the clearance of NETs mediated by...

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Detalles Bibliográficos
Autores principales: Dhawan, Umesh Kumar, Bhattacharya, Purbasha, Narayanan, Sriram, Manickam, Vijayprakash, Aggarwal, Ayush, Subramanian, Manikandan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454501/
https://www.ncbi.nlm.nih.gov/pubmed/34348488
http://dx.doi.org/10.1161/ATVBAHA.120.316389