Nicotine and its metabolite cotinine target MD2 and inhibit TLR4 signaling

Nicotine is the principal alkaloid of tobacco often manufactured into cigarettes and belongs to a highly addictive class of drugs. Nicotine attenuates the neuroinflammation induced by microglial activation. However, the molecular target(s) underlying anti-inflammatory action of nicotine has not been...

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Detalles Bibliográficos
Autores principales: Li, Hongyuan, Peng, Yinghua, Lin, Cong, Zhang, Xiaozheng, Zhang, Tianshu, Wang, Yibo, Li, Yuanpeng, Wu, Siru, Wang, Hongshuang, Hutchinson, Mark R., Watkins, Linda R., Wang, Xiaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454564/
https://www.ncbi.nlm.nih.gov/pubmed/34557761
http://dx.doi.org/10.1016/j.xinn.2021.100111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454564/
https://www.ncbi.nlm.nih.gov/pubmed/34557761
http://dx.doi.org/10.1016/j.xinn.2021.100111

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