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Innovative Irinotecan-Loaded Nanomicelles Will Enter Phase I Clinical Trial in 2021

Recent progress at the National Center for Nanoscience and Technology of China has enabled an extremely facile method to encapsulate irinotecan (CPT-11) into micelle-based nanoparticles (named as IH-NM). In preclinical study, compared with free CPT-11, IH-NM exhibited 1.56-fold higher maximum tolera...

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Detalles Bibliográficos
Autores principales: Li, Chan, Xu, Jing, Gan, Yaling, Liang, Xing-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454605/
https://www.ncbi.nlm.nih.gov/pubmed/34557721
http://dx.doi.org/10.1016/j.xinn.2020.100057