Renal ROCK Activation and Its Pharmacological Inhibition in Patients With Diabetes

Rho-associated coiled-coil-containing protein kinase (ROCK) is a serine/threonine kinase with essential roles in cytoskeletal functions. Substantial evidence implicates ROCK as a critical regulator in the inception and progression of diabetic nephropathy through a mechanism involving mesangial fibro...

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Detalles Bibliográficos
Autores principales: Matoba, Keiichiro, Sekiguchi, Kensuke, Nagai, Yosuke, Takeda, Yusuke, Takahashi, Hiroshi, Yokota, Tamotsu, Utsunomiya, Kazunori, Nishimura, Rimei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454778/
https://www.ncbi.nlm.nih.gov/pubmed/34557101
http://dx.doi.org/10.3389/fphar.2021.738121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454778/
https://www.ncbi.nlm.nih.gov/pubmed/34557101
http://dx.doi.org/10.3389/fphar.2021.738121

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