miR‐21 sustains CD28 signalling and low‐affinity T‐cell responses at the expense of self‐tolerance

OBJECTIVE: miR‐21 is highly expressed in iNKT and activated T cells, but its T‐cell autonomous functions are poorly defined. We sought to investigate the role of miR‐21 in the development and functions of T and iNKT cells, representing adaptive and innate‐like populations, respectively. METHODS: We...

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Detalles Bibliográficos
Autores principales: Fedeli, Maya, Kuka, Mirela, Finardi, Annamaria, Albano, Francesca, Viganò, Valentina, Iannacone, Matteo, Furlan, Roberto, Dellabona, Paolo, Casorati, Giulia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454917/
https://www.ncbi.nlm.nih.gov/pubmed/34584693
http://dx.doi.org/10.1002/cti2.1321

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454917/
https://www.ncbi.nlm.nih.gov/pubmed/34584693
http://dx.doi.org/10.1002/cti2.1321

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