Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling

Human herpesvirus 8 (HHV-8) is an oncogenic virus that enters cells by fusion of the viral and endosomal cellular membranes in a process mediated by viral surface glycoproteins. One of the cellular receptors hijacked by HHV-8 to gain access to cells is the EphA2 tyrosine kinase receptor, and the mec...

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Detalles Bibliográficos
Autores principales: Light, Taylor P., Brun, Delphine, Guardado-Calvo, Pablo, Pederzoli, Riccardo, Haouz, Ahmed, Neipel, Frank, Rey, Félix A., Hristova, Kalina, Backovic, Marija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454987/
https://www.ncbi.nlm.nih.gov/pubmed/34499637
http://dx.doi.org/10.1371/journal.pbio.3001392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454987/
https://www.ncbi.nlm.nih.gov/pubmed/34499637
http://dx.doi.org/10.1371/journal.pbio.3001392

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