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A machine learning strategy that leverages large datasets to boost statistical power in small-scale experiments

Machine learning methods have proven invaluable for increasing the sensitivity of peptide detection in proteomics experiments. Most modern tools, such as Percolator and PeptideProphet, use semi-supervised algorithms to learn models directly from the datasets that they analyze. Although these methods...

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Detalles Bibliográficos
Autores principales: Fondrie, William E., Noble, William S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455073/
https://www.ncbi.nlm.nih.gov/pubmed/32009418
http://dx.doi.org/10.1021/acs.jproteome.9b00780