N501Y mutation of spike protein in SARS-CoV-2 strengthens its binding to receptor ACE2

SARS-CoV-2 has been spreading around the world for the past year. Recently, several variants such as B.1.1.7 (alpha), B.1.351 (beta), and P.1 (gamma), which share a key mutation N501Y on the receptor-binding domain (RBD), appear to be more infectious to humans. To understand the underlying mechanism...

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Detalles Bibliográficos
Autores principales: Tian, Fang, Tong, Bei, Sun, Liang, Shi, Shengchao, Zheng, Bin, Wang, Zibin, Dong, Xianchi, Zheng, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455130/
https://www.ncbi.nlm.nih.gov/pubmed/34414884
http://dx.doi.org/10.7554/eLife.69091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455130/
https://www.ncbi.nlm.nih.gov/pubmed/34414884
http://dx.doi.org/10.7554/eLife.69091

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