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Controlling the topology of mammalian mitochondrial DNA

The genome of mitochondria, called mtDNA, is a small circular DNA molecule present at thousands of copies per human cell. MtDNA is packaged into nucleoprotein complexes called nucleoids, and the density of mtDNA packaging affects mitochondrial gene expression. Genetic processes such as transcription...

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Detalles Bibliográficos
Autores principales: Menger, Katja E., Rodríguez-Luis, Alejandro, Chapman, James, Nicholls, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455175/
https://www.ncbi.nlm.nih.gov/pubmed/34547213
http://dx.doi.org/10.1098/rsob.210168