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pH-Responsive Nanocomposite Based Hydrogels for the Controlled Delivery of Ticagrelor; In Vitro and In Vivo Approaches

BACKGROUND: Ticagrelor (TG), an antiplatelet drug is employed to treat patients with acute coronary syndrome, but its inadequate oral bioavailability due to poor solubility and low permeability restricts its effectiveness. PURPOSE: This contemporary work was aimed to design a novel pH-sensitive nano...

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Detalles Bibliográficos
Autores principales: Shahid, Nariman, Erum, Alia, Zaman, Muhammad, Tulain, Ume Ruqia, Shoaib, Qurat-ul-ain, Majeed, Abdul, Rasool, Muhammad F, Imran, Imran, Alshehri, Sultan, Noorani, Behnam, Alqahtani, Faleh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455181/
https://www.ncbi.nlm.nih.gov/pubmed/34556985
http://dx.doi.org/10.2147/IJN.S330186