Targeting EGFR sensitizes 5-Fu-resistant colon cancer cells through modification of the lncRNA-FGD5-AS1-miR-330-3p-Hexokinase 2 axis

5-Fluorouracil (5-Fu) is a widely applied anti-cancer agent against colorectal cancer (CRC), yet a number of CRC patients have developed resistance to 5-Fu-based chemotherapy. The epidermal growth factor receptor (EGFR) is recognized as an oncogene that promotes diverse cancer progresses. In additio...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Su-Jie, Ren, Sheng-Nan, Liu, Yi-Ting, Yan, Hong-Wei, Chen, Xue-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455313/
https://www.ncbi.nlm.nih.gov/pubmed/34589581
http://dx.doi.org/10.1016/j.omto.2021.06.012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455313/
https://www.ncbi.nlm.nih.gov/pubmed/34589581
http://dx.doi.org/10.1016/j.omto.2021.06.012

Ejemplares similares