Effects of adiposity on the human plasma proteome: observational and Mendelian randomisation estimates

BACKGROUND: Variation in adiposity is associated with cardiometabolic disease outcomes, but mechanisms leading from this exposure to disease are unclear. This study aimed to estimate effects of body mass index (BMI) on an extensive set of circulating proteins. METHODS: We used SomaLogic proteomic da...

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Detalles Bibliográficos
Autores principales: Goudswaard, Lucy J., Bell, Joshua A., Hughes, David A., Corbin, Laura J., Walter, Klaudia, Davey Smith, George, Soranzo, Nicole, Danesh, John, Di Angelantonio, Emanuele, Ouwehand, Willem H., Watkins, Nicholas A., Roberts, David J., Butterworth, Adam S., Hers, Ingeborg, Timpson, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455324/
https://www.ncbi.nlm.nih.gov/pubmed/34226637
http://dx.doi.org/10.1038/s41366-021-00896-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455324/
https://www.ncbi.nlm.nih.gov/pubmed/34226637
http://dx.doi.org/10.1038/s41366-021-00896-1

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