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Gene expression signatures predict response to therapy with growth hormone

Recombinant human growth hormone (r-hGH) is used as a therapeutic agent for disorders of growth including growth hormone deficiency (GHD) and Turner syndrome (TS). Treatment is costly and current methods to model response are inexact. GHD (n = 71) and TS patients (n = 43) were recruited to study res...

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Detalles Bibliográficos
Autores principales: Stevens, Adam, Murray, Philip, De Leonibus, Chiara, Garner, Terence, Koledova, Ekaterina, Ambler, Geoffrey, Kapelari, Klaus, Binder, Gerhard, Maghnie, Mohamad, Zucchini, Stefano, Bashnina, Elena, Skorodok, Julia, Yeste, Diego, Belgorosky, Alicia, Siguero, Juan-Pedro Lopez, Coutant, Regis, Vangsøy-Hansen, Eirik, Hagenäs, Lars, Dahlgren, Jovanna, Deal, Cheri, Chatelain, Pierre, Clayton, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455334/
https://www.ncbi.nlm.nih.gov/pubmed/34045667
http://dx.doi.org/10.1038/s41397-021-00237-5