Cargando…

Gene expression signatures predict response to therapy with growth hormone

Recombinant human growth hormone (r-hGH) is used as a therapeutic agent for disorders of growth including growth hormone deficiency (GHD) and Turner syndrome (TS). Treatment is costly and current methods to model response are inexact. GHD (n = 71) and TS patients (n = 43) were recruited to study res...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stevens, Adam, Murray, Philip, De Leonibus, Chiara, Garner, Terence, Koledova, Ekaterina, Ambler, Geoffrey, Kapelari, Klaus, Binder, Gerhard, Maghnie, Mohamad, Zucchini, Stefano, Bashnina, Elena, Skorodok, Julia, Yeste, Diego, Belgorosky, Alicia, Siguero, Juan-Pedro Lopez, Coutant, Regis, Vangsøy-Hansen, Eirik, Hagenäs, Lars, Dahlgren, Jovanna, Deal, Cheri, Chatelain, Pierre, Clayton, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455334/ https://www.ncbi.nlm.nih.gov/pubmed/34045667 http://dx.doi.org/10.1038/s41397-021-00237-5

Ejemplares similares

GH deficiency status combined with GH receptor polymorphism affects response to GH in children
por: Valsesia, Armand, et al.
Publicado: (2015)

A pharmacogenomic approach to the treatment of children with GH deficiency or Turner syndrome
por: Clayton, P, et al.
Publicado: (2013)

Effect of summer daylight exposure and genetic background on growth in growth hormone-deficient children
por: De Leonibus, C, et al.
Publicado: (2016)

Growth, Endocrine Features, and Growth Hormone Treatment in Noonan Syndrome
por: Dahlgren, Jovanna, et al.
Publicado: (2022)

Validating genetic markers of response to recombinant human growth hormone in children with growth hormone deficiency and Turner syndrome: the PREDICT validation study
por: Stevens, Adam, et al.
Publicado: (2016)

Pharmacogenomics of insulin-like growth factor-I generation during GH treatment in children with GH deficiency or Turner syndrome
por: Stevens, A, et al.
Publicado: (2014)

GH Responsiveness in Children With Noonan Syndrome Compared to Turner Syndrome
por: Dahlgren, Jovanna, et al.
Publicado: (2021)

Short Stature Diagnosis and Referral
por: Maghnie, Mohamad, et al.
Publicado: (2018)

The DICER1 familial cancer syndrome: clinical and molecular update
por: Deal, Cheri
Publicado: (2013)

Is There An Overlap Between Eating Disorders and Neurodevelopmental Disorders in Children with Obesity?
por: Wentz, Elisabet, et al.
Publicado: (2019)

Longitudinal Sex Steroid Data in Relation to Birth Weight in Preterm Boys
por: Allvin, Kerstin, et al.
Publicado: (2022)

New Horizons in Short Children Born Small for Gestational Age
por: Netchine, Irène, et al.
Publicado: (2021)

Adrenal and Gonadal Activity, Androgen Concentrations, and Adult Height Outcomes in Boys With Silver-Russell Syndrome
por: Kvernebo Sunnergren, Kjersti, et al.
Publicado: (2019)

Topline Results of the CARE-PWS Phase 3 Study: Intranasal Carbetocin Improves Hyperphagia and Anxiety and Distress Symptoms in Prader-Willi Syndrome (PWS)
por: Ryman, Davis, et al.
Publicado: (2021)

Salivary microflora and mode of delivery: a prospective case control study
por: Boustedt, Katarina, et al.
Publicado: (2015)

Patient Acceptance, Ease of Use, and Preference for Norditropin NordiFlex with NordiFlex PenMate: Results from an Open-Label, User Survey of Everyday Use
por: Hokken-Koelega, Anita, et al.
Publicado: (2011)

Case report: ADHD and prognosis in tyrosinemia type 1
por: Barone, Helene, et al.
Publicado: (2023)

Clinical charts for surveillance of growth and body proportion development in achondroplasia and examples of their use
por: Neumeyer, Luitgard, et al.
Publicado: (2020)

Safety Outcomes During Pediatric GH Therapy: Final Results From the Prospective GeNeSIS Observational Program
por: Child, Christopher J, et al.
Publicado: (2018)

PMON336 Pfizer Registry of Outcomes in Growth hormone RESearch (PROGRES): A multi-country, non-interventional, prospective, cohort study of patients receiving human growth hormone treatments under routine clinical care
por: Geffner, Mitchell E, et al.
Publicado: (2022)

The first-year growth response to growth hormone treatment predicts the long-term prepubertal growth response in children
por: Kriström, Berit, et al.
Publicado: (2009)

High Physiological Omega-3 Fatty Acid Supplementation Affects Muscle Fatty Acid Composition and Glucose and Insulin Homeostasis in Obese Adolescents
por: Dangardt, Frida, et al.
Publicado: (2012)

Important Tools for Use by Pediatric Endocrinologists in the Assessment of Short Stature
por: Labarta, José I., et al.
Publicado: (2021)

An eHealth Framework for Managing Pediatric Growth Disorders and Growth Hormone Therapy
por: Dimitri, Paul, et al.
Publicado: (2021)

Associations between pain, health, and lifestyle factors in 10-year-old boys and girls from a Swedish birth cohort
por: Malmborg, Julia S., et al.
Publicado: (2023)

Oral Iron for Prevention and Treatment of Rickets and Osteomalacia in Autosomal Dominant Hypophosphatemia
por: Högler, Wolfgang, et al.
Publicado: (2019)

Models predicting the growth response to growth hormone treatment in short children independent of GH status, birth size and gestational age
por: Dahlgren, Jovanna, et al.
Publicado: (2007)

Serum prolactin levels in a uremic child: effects of bilateral nephrectomy and kidney transplantation
por: Rondeau, Geneviève, et al.
Publicado: (2011)

Insulin Growth Factor 1 Predicts Central Precocious Puberty in Girls 6 to 8 Years-Old: A Retrospective Study
por: Escagedo, Patricia Diaz, et al.
Publicado: (2021)

A proteomic approach identified growth hormone-dependent nutrition markers in children with idiopathic short stature
por: Hellgren, Gunnel, et al.
Publicado: (2008)

Influence of neighbourhood purchasing power on breastfeeding at four months of age: a Swedish population-based cohort study
por: Almquist-Tangen, Gerd, et al.
Publicado: (2013)

Overweight at four years of age in a Swedish birth cohort: influence of neighbourhood-level purchasing power
por: Roswall, Josefine, et al.
Publicado: (2016)

Different thresholds of tissue-specific dose-responses to growth hormone in short prepubertal children
por: Decker, Ralph, et al.
Publicado: (2012)

Cardiovascular safety of growth hormone treatment in Noonan syndrome: real-world evidence
por: Romano, Alicia, et al.
Publicado: (2021)

Pharmacogenomics applied to recombinant human growth hormone responses in children with short stature
por: Stevens, Adam, et al.
Publicado: (2021)

Hyperestrogenism Affects Adult Height Outcome in Growth Hormone Treated Boys With Silver-Russell Syndrome
por: Kvernebo-Sunnergren, Kjersti, et al.
Publicado: (2018)

Depression, anxiety, and suicidal ideation in young adults 5 years after undergoing bariatric surgery as adolescents
por: Järvholm, Kajsa, et al.
Publicado: (2020)

SUN-244 Birth and Perinatal Characteristics of Children with Congenital GH Deficiency (GHD) Due to Abnormal Pituitary Development: Data from a Prospective, Multinational Observational Study
por: Child, Christopher, et al.
Publicado: (2019)

Growth Hormone Dose Modulation and Final Height in Short Children Born Small for Gestational Age: French Real-Life Data
por: Coutant, Régis, et al.
Publicado: (2023)

Mutation in NRAS in familial Noonan syndrome – case report and review of the literature
por: Ekvall, Sara, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_83i87n33fhcglvci5cfgsvp6hq