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The receptor-type protein tyrosine phosphatase CD45 promotes onset and severity of IL-1β–mediated autoinflammatory osteomyelitis

A number of human autoinflammatory diseases manifest with severe inflammatory bone destruction. Mouse models of these diseases represent valuable tools that help us to understand molecular mechanisms triggering this bone autoinflammation. The Pstpip2(cmo) mouse strain is among the best characterized...

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Detalles Bibliográficos
Autores principales: Kralova, Jarmila, Pavliuchenko, Nataliia, Fabisik, Matej, Ilievova, Kristyna, Spoutil, Frantisek, Prochazka, Jan, Pokorna, Jana, Sedlacek, Radislav, Brdicka, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455366/
https://www.ncbi.nlm.nih.gov/pubmed/34461100
http://dx.doi.org/10.1016/j.jbc.2021.101131