Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans

BACKGROUND AND AIMS: The trigger hypothesis opens the possibility of anti-flare initiation therapies by stating that ulcerative colitis (UC) flares originate from inadequate responses to acute mucosal injuries. However, experimental evidence is restricted by a limited use of suitable human models. W...

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Detalles Bibliográficos
Autores principales: Seidelin, Jakob Benedict, Bahl, Martin Iain, Licht, Tine Rask, Mead, Benjamin E., Karp, Jeffrey M., Johansen, Jens Vilstrup, Riis, Lene Buhl, Galera, Marina Ramírez, Woetmann, Anders, Bjerrum, Jacob Tveiten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455368/
https://www.ncbi.nlm.nih.gov/pubmed/34118489
http://dx.doi.org/10.1016/j.jcmgh.2021.06.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455368/
https://www.ncbi.nlm.nih.gov/pubmed/34118489
http://dx.doi.org/10.1016/j.jcmgh.2021.06.002

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