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Acute Experimental Barrier Injury Triggers Ulcerative Colitis–Specific Innate Hyperresponsiveness and Ulcerative Colitis–Type Microbiome Changes in Humans
BACKGROUND AND AIMS: The trigger hypothesis opens the possibility of anti-flare initiation therapies by stating that ulcerative colitis (UC) flares originate from inadequate responses to acute mucosal injuries. However, experimental evidence is restricted by a limited use of suitable human models. W...
Autores principales: | Seidelin, Jakob Benedict, Bahl, Martin Iain, Licht, Tine Rask, Mead, Benjamin E., Karp, Jeffrey M., Johansen, Jens Vilstrup, Riis, Lene Buhl, Galera, Marina Ramírez, Woetmann, Anders, Bjerrum, Jacob Tveiten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455368/ https://www.ncbi.nlm.nih.gov/pubmed/34118489 http://dx.doi.org/10.1016/j.jcmgh.2021.06.002 |
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