Secretory helpers for enhanced production of heterologous proteins in Yarrowia lipolytica

Depending on the suboptimal factor, the target protein secretion can be over 1000-fold below the theoretical maximum. The bottlenecks may be alleviated by co-overexpression of “secretory helpers” (SHs). Here we proposed twelve SHs, functionally spanning the whole transcription-translation-translocat...

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Detalles Bibliográficos
Autores principales: Korpys-Woźniak, Paulina, Kubiak, Piotr, Celińska, Ewelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455373/
https://www.ncbi.nlm.nih.gov/pubmed/34584852
http://dx.doi.org/10.1016/j.btre.2021.e00669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455373/
https://www.ncbi.nlm.nih.gov/pubmed/34584852
http://dx.doi.org/10.1016/j.btre.2021.e00669

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