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Secretory helpers for enhanced production of heterologous proteins in Yarrowia lipolytica
Depending on the suboptimal factor, the target protein secretion can be over 1000-fold below the theoretical maximum. The bottlenecks may be alleviated by co-overexpression of “secretory helpers” (SHs). Here we proposed twelve SHs, functionally spanning the whole transcription-translation-translocat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455373/ https://www.ncbi.nlm.nih.gov/pubmed/34584852 http://dx.doi.org/10.1016/j.btre.2021.e00669 |