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The phosphatase PRL-3 affects intestinal homeostasis by altering the crypt cell composition

Expression of the phosphatase of regenerating liver-3 (PRL-3) is known to promote tumor growth in gastrointestinal adenocarcinomas, and the incidence of tumor formation upon inflammatory events correlates with PRL-3 levels in mouse models. These carcinomas and their onset are associated with the imp...

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Detalles Bibliográficos
Autores principales: Rubio, Teresa, Weyershaeuser, Judith, Montero, Marta G., Hoffmann, Andreas, Lujan, Pablo, Jechlinger, Martin, Sotillo, Rocio, Köhn, Maja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455404/
https://www.ncbi.nlm.nih.gov/pubmed/34129057
http://dx.doi.org/10.1007/s00109-021-02097-9