Preparation of monovalent follistatin-like 3-Fc-fusion protein and evaluation of its effects on muscle mass in mice

Follistatin-like 3 (FSTL3) is an endogenous antagonist against transforming growth factor-β family ligands. Monovalent FSTL3-Fc fusion protein (mono-FSTL3-Fc) generated with knobs-into-holes technology overcomes limitations of current anti-myostatin therapies. We have developed a facile protocol for...

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Detalles Bibliográficos
Autores principales: Ozawa, Takayuki, Miyazono, Kohei, Morikawa, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455479/
https://www.ncbi.nlm.nih.gov/pubmed/34585166
http://dx.doi.org/10.1016/j.xpro.2021.100839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455479/
https://www.ncbi.nlm.nih.gov/pubmed/34585166
http://dx.doi.org/10.1016/j.xpro.2021.100839

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