Inhibitor of DNA binding 2 (Id2) mediates microtubule polymerization in the brain by regulating αK40 acetylation of α-tubulin

Acetylation of α-tubulin lysine 40 (αK40) contributes to microtubule (MT) stability and is essential for neuronal development and function, whereas excessive αK40 deacetylation is observed in neurodegenerative disorders including Alzheimer’s disease (AD). Here we identified inhibitor of DNA binding...

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Detalles Bibliográficos
Autores principales: Yun, Taegwan, Ko, Hyo Rim, Jo, Dong-Gyu, Park, Kye Won, Cho, Sung-Woo, Kim, Jihoe, Ahn, Jee-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455547/
https://www.ncbi.nlm.nih.gov/pubmed/34548475
http://dx.doi.org/10.1038/s41420-021-00652-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455547/
https://www.ncbi.nlm.nih.gov/pubmed/34548475
http://dx.doi.org/10.1038/s41420-021-00652-4

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