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Inhibitor of DNA binding 2 (Id2) mediates microtubule polymerization in the brain by regulating αK40 acetylation of α-tubulin
Acetylation of α-tubulin lysine 40 (αK40) contributes to microtubule (MT) stability and is essential for neuronal development and function, whereas excessive αK40 deacetylation is observed in neurodegenerative disorders including Alzheimer’s disease (AD). Here we identified inhibitor of DNA binding...
Autores principales: | Yun, Taegwan, Ko, Hyo Rim, Jo, Dong-Gyu, Park, Kye Won, Cho, Sung-Woo, Kim, Jihoe, Ahn, Jee-Yin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455547/ https://www.ncbi.nlm.nih.gov/pubmed/34548475 http://dx.doi.org/10.1038/s41420-021-00652-4 |
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