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Pathways to Parkinson’s disease: a spotlight on 14-3-3 proteins

14-3-3s represent a family of highly conserved 30 kDa acidic proteins. 14-3-3s recognize and bind specific phospho-sequences on client partners and operate as molecular hubs to regulate their activity, localization, folding, degradation, and protein–protein interactions. 14-3-3s are also associated...

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Detalles Bibliográficos
Autores principales: Giusto, E., Yacoubian, T. A., Greggio, E., Civiero, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455551/
https://www.ncbi.nlm.nih.gov/pubmed/34548498
http://dx.doi.org/10.1038/s41531-021-00230-6