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Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential

SARS-CoV-2 is the causative agent behind the COVID-19 pandemic, responsible for over 170 million infections, and over 3.7 million deaths worldwide. Efforts to test, treat and vaccinate against this pathogen all benefit from an improved understanding of the basic biology of SARS-CoV-2. Both viral and...

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Detalles Bibliográficos
Autores principales: Meyer, Bjoern, Chiaravalli, Jeanne, Gellenoncourt, Stacy, Brownridge, Philip, Bryne, Dominic P., Daly, Leonard A., Grauslys, Arturas, Walter, Marius, Agou, Fabrice, Chakrabarti, Lisa A., Craik, Charles S., Eyers, Claire E., Eyers, Patrick A., Gambin, Yann, Jones, Andrew R., Sierecki, Emma, Verdin, Eric, Vignuzzi, Marco, Emmott, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455558/
https://www.ncbi.nlm.nih.gov/pubmed/34548480
http://dx.doi.org/10.1038/s41467-021-25796-w