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Transferrin-Pep63-liposomes accelerate the clearance of Aβ and rescue impaired synaptic plasticity in early Alzheimer’s disease models

Alzheimer’s disease (AD) is characterized by aberrant accumulation of extracellular β-amyloid (Aβ) peptides in the brain. Soluble Aβ oligomers are thought to be the most neurotoxic species and are correlated with cognitive dysfunction in early AD. However, there is still no effective treatment so fa...

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Detalles Bibliográficos
Autores principales: Yang, Xiu, Li, Xu, Liu, Le, Chen, Yuan-Hao, You, Yue, Gao, Yin, Liu, Yue-Ying, Yang, Li, Tong, Kun, Chen, Di-Shi, Hao, Jing-Ru, Sun, Nan, Zhao, Zi-Ming, Gao, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455582/
https://www.ncbi.nlm.nih.gov/pubmed/34548476
http://dx.doi.org/10.1038/s41420-021-00639-1