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TDP-43 regulates GAD1 mRNA splicing and GABA signaling in Drosophila CNS
Alterations in the function of the RNA-binding protein TDP-43 are largely associated with the pathogenesis of amyotrophic lateral sclerosis (ALS), a devastating disease of the human motor system that leads to motoneurons degeneration and reduced life expectancy by molecular mechanisms not well known...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455590/ https://www.ncbi.nlm.nih.gov/pubmed/34548578 http://dx.doi.org/10.1038/s41598-021-98241-z |