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NAD(+) augmentation with nicotinamide riboside improves lymphoid potential of Atm(−/−) and old mice HSCs

NAD(+) supplementation has significant benefits in compromised settings, acting largely through improved mitochondrial function and DNA repair. Elevating NAD(+) to physiological levels has been shown to improve the function of some adult stem cells, with implications that these changes will lead to...

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Detalles Bibliográficos
Autores principales: Zong, Le, Tanaka-Yano, Mayuri, Park, Bongsoo, Yanai, Hagai, Turhan, Ferda T., Croteau, Deborah L., Tian, Jane, Fang, Evandro F., Bohr, Vilhelm A., Beerman, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455618/
https://www.ncbi.nlm.nih.gov/pubmed/34548492
http://dx.doi.org/10.1038/s41514-021-00078-3