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A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis

Herpes simplex virus 1 (HSV-1) is responsible for herpes simplex virus encephalitis (HSE), associated with a 70% mortality rate in the absence of treatment. Despite intravenous treatment with acyclovir, mortality remains significant, highlighting the need for new anti-herpetic agents. Herein, we des...

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Detalles Bibliográficos
Autores principales: Uyar, Olus, Plante, Pier-Luc, Piret, Jocelyne, Venable, Marie-Christine, Carbonneau, Julie, Corbeil, Jacques, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455621/
https://www.ncbi.nlm.nih.gov/pubmed/34548521
http://dx.doi.org/10.1038/s41598-021-98047-z