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A novel bioluminescent herpes simplex virus 1 for in vivo monitoring of herpes simplex encephalitis
Herpes simplex virus 1 (HSV-1) is responsible for herpes simplex virus encephalitis (HSE), associated with a 70% mortality rate in the absence of treatment. Despite intravenous treatment with acyclovir, mortality remains significant, highlighting the need for new anti-herpetic agents. Herein, we des...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455621/ https://www.ncbi.nlm.nih.gov/pubmed/34548521 http://dx.doi.org/10.1038/s41598-021-98047-z |