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Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis

Programmed necrosis, such as necroptosis and pyroptosis, is a highly pro-inflammatory cellular event that is associated with chronic inflammation. Although there are various triggers of pyroptosis and necroptosis in autoimmune tissue inflammation and subsequent lytic forms of cell death release abun...

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Detalles Bibliográficos
Autores principales: Takeuchi, Yusuke, Ohara, Daiya, Watanabe, Hitomi, Sakaguchi, Noriko, Sakaguchi, Shimon, Kondoh, Gen, Morinobu, Akio, Mimori, Tsuneyo, Hirota, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455622/
https://www.ncbi.nlm.nih.gov/pubmed/34548542
http://dx.doi.org/10.1038/s41598-021-98145-y