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Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis
Programmed necrosis, such as necroptosis and pyroptosis, is a highly pro-inflammatory cellular event that is associated with chronic inflammation. Although there are various triggers of pyroptosis and necroptosis in autoimmune tissue inflammation and subsequent lytic forms of cell death release abun...
Autores principales: | Takeuchi, Yusuke, Ohara, Daiya, Watanabe, Hitomi, Sakaguchi, Noriko, Sakaguchi, Shimon, Kondoh, Gen, Morinobu, Akio, Mimori, Tsuneyo, Hirota, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455622/ https://www.ncbi.nlm.nih.gov/pubmed/34548542 http://dx.doi.org/10.1038/s41598-021-98145-y |
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