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Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice

Estrogen levels decline in both sexes with age, but more dramatically in females. Activation of the Wnt/β-catenin signaling pathway is central to the regulation of bone mass accrual and maintenance and in response to mechanical loading. Using the ovariectomized mouse model we examined the effect of...

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Detalles Bibliográficos
Autores principales: Jackson, Erica, Lara-Castillo, Nuria, Akhter, Mohammed P., Dallas, Mark, Scott, JoAnna M., Ganesh, Thiagarajan, Johnson, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455641/
https://www.ncbi.nlm.nih.gov/pubmed/34584905
http://dx.doi.org/10.1016/j.bonr.2021.101129