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Inhibition of cardiac PERK signaling promotes peripartum cardiac dysfunction
Peripartum cardiomyopathy (PPCM) is a life-threatening heart failure occurring in the peripartum period. Although mal-angiogenesis, induced by the 16-kDa N-terminal prolactin fragment (16 K PRL), is involved in the pathogenesis, the effect of full-length prolactin (23 K PRL) is poorly understood. We...
Autores principales: | Shimizu, Takashi, Taguchi, Akashi, Higashijima, Yoshiki, Kanki, Yasuharu, Nakaki, Ryo, Urade, Yoshihiro, Wada, Youichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455649/ https://www.ncbi.nlm.nih.gov/pubmed/34548576 http://dx.doi.org/10.1038/s41598-021-98344-7 |
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