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Affinity Proteomics and Deglycoproteomics Uncover Novel EDEM2 Endogenous Substrates and an Integrative ERAD Network

Various pathologies result from disruptions to or stress of endoplasmic reticulum (ER) homeostasis, such as Parkinson's disease and most neurodegenerative illnesses, diabetes, pulmonary fibrosis, viral infections, and cancers. A critical process in maintaining ER homeostasis is the selection of...

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Detalles Bibliográficos
Autores principales: Munteanu, Cristian V.A., Chirițoiu, Gabriela N., Chirițoiu, Marioara, Ghenea, Simona, Petrescu, Andrei-Jose, Petrescu, Ştefana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455867/
https://www.ncbi.nlm.nih.gov/pubmed/34332121
http://dx.doi.org/10.1016/j.mcpro.2021.100125