Impacts of NF1 Gene Mutations and Genetic Modifiers in Neurofibromatosis Type 1

Neurofibromatosis type 1 (NF1) is a tumor predisposition genetic disorder that directly affects more than 1 in 3,000 individuals worldwide. It results from mutations of the NF1 gene and shows almost complete penetrance. NF1 patients show high phenotypic variabilities, including cafe-au-lait macules,...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wei, Cheng-Jiang, Cui, Xi-Wei, Li, Yue-Hua, Gu, Yi-Hui, Gu, Bin, Li, Qing-Feng, Wang, Zhi-Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455870/
https://www.ncbi.nlm.nih.gov/pubmed/34566848
http://dx.doi.org/10.3389/fneur.2021.704639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455870/
https://www.ncbi.nlm.nih.gov/pubmed/34566848
http://dx.doi.org/10.3389/fneur.2021.704639

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