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Dexmedetomidine Relieves Neuropathic Pain in Rats With Chronic Constriction Injury via the Keap1–Nrf2 Pathway

This study aimed to determine the role of dexmedetomidine (Dex) in neuropathic pain (NP) after chronic constriction injury (CCI) in a rat model as well as its underlying mechanism. First, a CCI rat model was established. After treatment with Dex, the severity of NP was ascertained by monitoring paw...

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Detalles Bibliográficos
Autores principales: Liu, Yatao, Liu, Wei, Wang, Xiao-Qing, Wan, Zhan-Hai, Liu, Yong-Qiang, Zhang, Meng-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455886/
https://www.ncbi.nlm.nih.gov/pubmed/34568327
http://dx.doi.org/10.3389/fcell.2021.714996