Cryptococcus neoformans Δsgl1 Vaccination Requires Either CD4(+) or CD8(+) T Cells for Complete Host Protection

Cryptococcus neoformans is a fungal pathogen causing life-threatening meningoencephalitis in susceptible individuals. Fungal vaccine development has been hampered by the fact that cryptococcosis occurs during immunodeficiency. We previously reported that a C. neoformans mutant (Δsgl1) accumulating s...

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Detalles Bibliográficos
Autores principales: Normile, Tyler G., Rella, Antonella, Del Poeta, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455912/
https://www.ncbi.nlm.nih.gov/pubmed/34568097
http://dx.doi.org/10.3389/fcimb.2021.739027

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455912/
https://www.ncbi.nlm.nih.gov/pubmed/34568097
http://dx.doi.org/10.3389/fcimb.2021.739027

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