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Cryptococcus neoformans Δsgl1 Vaccination Requires Either CD4(+) or CD8(+) T Cells for Complete Host Protection
Cryptococcus neoformans is a fungal pathogen causing life-threatening meningoencephalitis in susceptible individuals. Fungal vaccine development has been hampered by the fact that cryptococcosis occurs during immunodeficiency. We previously reported that a C. neoformans mutant (Δsgl1) accumulating s...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455912/ https://www.ncbi.nlm.nih.gov/pubmed/34568097 http://dx.doi.org/10.3389/fcimb.2021.739027 |