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Degenerate CD8 Epitopes Mapping to Structurally Constrained Regions of the Spike Protein: A T Cell-Based Way-Out From the SARS-CoV-2 Variants Storm

There is an urgent need for new generation anti-SARS-Cov-2 vaccines in order to increase the efficacy of immunization and its broadness of protection against viral variants that are continuously arising and spreading. The effect of variants on protective immunity afforded by vaccination has been mos...

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Detalles Bibliográficos
Autores principales: Boni, Carolina, Cavazzini, Davide, Bolchi, Angelo, Rossi, Marzia, Vecchi, Andrea, Tiezzi, Camilla, Barili, Valeria, Fisicaro, Paola, Ferrari, Carlo, Ottonello, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455995/
https://www.ncbi.nlm.nih.gov/pubmed/34566990
http://dx.doi.org/10.3389/fimmu.2021.730051