A Conserved Role for LRRK2 and Roco Proteins in the Regulation of Mitochondrial Activity

Parkinson’s Disease (PD) is the second most common neurodegenerative disease world-wide. Mutations in the multidomain protein Leucine Rich Repeat Kinase 2 (LRRK2) are the most frequent cause of hereditary PD. Furthermore, recent data suggest that independent of mutations, increased kinase activity o...

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Detalles Bibliográficos
Autores principales: Rosenbusch, Katharina E., Oun, Asmaa, Sanislav, Oana, Lay, Sui T., Keizer-Gunnink, Ineke, Annesley, Sarah J., Fisher, Paul R., Dolga, Amalia M., Kortholt, Arjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455996/
https://www.ncbi.nlm.nih.gov/pubmed/34568343
http://dx.doi.org/10.3389/fcell.2021.734554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455996/
https://www.ncbi.nlm.nih.gov/pubmed/34568343
http://dx.doi.org/10.3389/fcell.2021.734554

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