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Common Threads: Aphidicolin-Inducible and Folate-Sensitive Fragile Sites in the Human Genome

The human genome has many chromosomal regions that are fragile, demonstrating chromatin breaks, gaps, or constrictions on exposure to replication stress. Common fragile sites (CFSs) are found widely distributed in the population, with the largest subset of these sites being induced by aphidicolin (A...

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Detalles Bibliográficos
Autores principales: Lokanga, Rachel Adihe, Kumari, Daman, Usdin, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456018/
https://www.ncbi.nlm.nih.gov/pubmed/34567068
http://dx.doi.org/10.3389/fgene.2021.708860