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Prediction and identification of synergistic compound combinations against pancreatic cancer cells
Resistance to current therapies is common for pancreatic cancer and hence novel treatment options are urgently needed. In this work, we developed and validated a computational method to select synergistic compound combinations based on transcriptomic profiles from both the disease and compound side,...
Autores principales: | KalantarMotamedi, Yasaman, Choi, Ran Joo, Koh, Siang-Boon, Bramhall, Jo L., Fan, Tai-Ping, Bender, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456050/ https://www.ncbi.nlm.nih.gov/pubmed/34585118 http://dx.doi.org/10.1016/j.isci.2021.103080 |
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