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Phagocytosis by stroma confounds coculture studies

Signals provided by the microenvironment can modify and circumvent pathway activities that are therapeutically targeted by drugs. Bone marrow stromal cell coculture models are frequently used to study the influence of the bone marrow niche on ex vivo drug response. Here, we show that mesenchymal str...

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Detalles Bibliográficos
Autores principales: Herbst, Sophie A., Stolarczyk, Marta, Becirovic, Tina, Czernilofsky, Felix, Liu, Yi, Kolb, Carolin, Knoll, Mareike, Herling, Marco, Müller-Tidow, Carsten, Dietrich, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456054/
https://www.ncbi.nlm.nih.gov/pubmed/34585113
http://dx.doi.org/10.1016/j.isci.2021.103062